General Information of Xenobiotics (ID: XEO00715)
Xenobiotics Name
L-745337
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Preclinical/Patented Drug
Structure
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3D MOL 2D MOL
PubChem CID
9799453
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Prostaglandin G/H synthase 2 (COX-2) DME Info IC50 = 0.02 microM [1]
References
1 1,2-Diarylcyclopentenes as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents. J Med Chem. 1995 Oct 27;38(22):4570-8.

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