General Information of Xenobiotics (ID: XEO00716)
Xenobiotics Name
STX140
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Preclinical/Patented Drug
Structure
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3D MOL 2D MOL
PubChem CID
9804302
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Carbonic anhydrase II (CA2) DME Info Homo sapiens [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Carbonic anhydrase II (CA2) DME Info IC50 = 0.379 microM [1], [2]
References
1 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. J Med Chem. 2006 Dec 28;49(26):7683-96.
2 Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents. J Med Chem. 2008 Mar 13;51(5):1295-308.

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