Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00728)
Xenobiotics Name
AM-580
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Preclinical/Patented Drug
Structure
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3D MOL 2D MOL
PubChem CID
2126
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Adenosine aminohydrolase (ADA) DME Info Homo sapiens [1]
Aromatase (CYP19A1) DME Info Homo sapiens [2]
Retinoic acid 4-hydroxylase 26A1 (CYP26A1) DME Info Homo sapiens [3]
Short-chain dehydrogenase/reductase retSDR1 (DHRS3) DME Info Homo sapiens [1]
Beta-glucuronidase (GUSB) DME Info Homo sapiens [1]
Transglutaminase H (TGM2) DME Info Homo sapiens [4]
References
1 PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells. J Exp Med. 2006 Oct 2;203(10):2351-62.
2 Trialkyltin compounds bind retinoid X receptor to alter human placental endocrine functions. Mol Endocrinol. 2005 Oct;19(10):2502-16.
3 Induction of the cytochrome P450 gene CYP26 during mucous cell differentiation of normal human tracheobronchial epithelial cells. Mol Pharmacol. 2000 Sep;58(3):483-90.
4 New benzoic acid derivatives with retinoid activity: lack of direct correlation between biological activity and binding to cellular retinoic acid binding protein. Cancer Res. 1987 Jul 1;47(13):3523-7.

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