Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00751)
Xenobiotics Name
Cocaine hydrochloride
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=656832"></iframe>
3D MOL 2D MOL
PubChem CID
656832
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Carboxylesterase 2 (CES2) DME Info Homo sapiens [1]
Cytochrome P450 2C8 (CYP2C8) DME Info Homo sapiens [2]
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [2]
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [3]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [1]
References
1 Transcriptional profiling in the human prefrontal cortex: evidence for two activational states associated with cocaine abuse. Pharmacogenomics J. 2003;3(1):27-40.
2 Down-regulation of astroglial CYP2C, glucocorticoid receptor and constitutive androstane receptor genes in response to cocaine in human U373 MG astrocytoma cells. Toxicol Lett. 2005 Dec 15;159(3):203-11.
3 Molecular analysis of cocaine-induced endothelial dysfunction: role of endothelin-1 and nitric oxide. Cardiovasc Toxicol. 2008 Dec;8(4):161-71.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.