Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00757)
Xenobiotics Name	Apple polyphenol extract
Xenobiotics Type	Natural Product(s), Extract(s) or Medicine(s)
Classification	Plant Extract
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
	Vitamin D(3) 24-hydroxylase (CYP24A1)	DME Info	Homo sapiens	[1]
	Leukotriene B4 omega-hydroxylase (CYP4F3)	DME Info	Homo sapiens	[2]
	Glutathione S-transferase pi (GSTP1)	DME Info	Homo sapiens	[2]
	Microsomal glutathione S-transferase 2 (MGST2)	DME Info	Homo sapiens	[2]
	UDP-glucuronosyltransferase 2B7 (UGT2B7)	DME Info	Homo sapiens	[1]

References
1	Apple polyphenols modulate expression of selected genes related to toxicological defence and stress response in human colon adenoma cells. Int J Cancer. 2008 Jun 15;122(12):2647-55.
2	Apple flavonoids inhibit growth of HT29 human colon cancer cells and modulate expression of genes involved in the biotransformation of xenobiotics. Mol Carcinog. 2006 Mar;45(3):164-74.

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