Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00826)
Xenobiotics Name
Mangifera indica extract
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Plant Extract
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [1], [2]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [3]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DME Info Homo sapiens [3], [4]
References
1 Quercetin protected isolated human erythrocytes against mancozeb-induced oxidative stress. Toxicol Ind Health. 2014 Jul;30(6):561-9.
2 Protective effects of lupeol against mancozeb-induced genotoxicity in cultured human lymphocytes. Phytomedicine. 2016 Jun 15;23(7):714-24.
3 Gene expression profiling of human primary astrocytes exposed to manganese chloride indicates selective effects on several functions of the cells. Neurotoxicology. 2007 May;28(3):478-89.
4 Induction of COX-2 in human airway cells by manganese: role of PI3K/PKB, p38 MAPK, PKCs, Src, and glutathione depletion. Toxicol In Vitro. 2009 Feb;23(1):120-6.

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