Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00873)
Xenobiotics Name
Alpha-linolenic acid
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5280934"></iframe>
3D MOL 2D MOL
PubChem CID
5280934
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [1]
Mephenytoin 4-hydroxylase (CYP2C19) DME Info Homo sapiens [1]
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [1]
Cytochrome P450 2E1 (CYP2E1) DME Info Homo sapiens [1]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Butyrylcholine esterase (BCHE) DME Info Homo sapiens [2]
Cytochrome P450 2A6 (CYP2A6) DME Info Homo sapiens [3]
Glutathione S-transferase alpha-1 (GSTA1) DME Info Homo sapiens [3]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [4]
References
1 The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes. Life Sci. 2006 Nov 25;79(26):2432-40.
2 Butyrylcholinesterase expression is regulated by fatty acids in HepG2 cells. Chem Biol Interact. 2016 Nov 25;259(Pt B):276-281.
3 High fat diet-induced hepatic 18-carbon fatty acids accumulation up-regulates CYP2A5/CYP2A6 via NF-E2-related factor 2. Front Pharmacol. 2017 May 15;8:233.
4 Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation. Br J Nutr. 2006 Nov;96(5):811-9.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.