Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00955)
Xenobiotics Name
Prochloraz
Xenobiotics Type
Fungicide(s), Herbicide(s) or Insecticide(s)
Classification
Fungicide
Structure
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3D MOL 2D MOL
PubChem CID
73665
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Steroid 11-beta-hydroxylase (CYP11B1) DME Info Homo sapiens [1], [2]
Steroid 17-alpha-monooxygenase (CYP17A1) DME Info Homo sapiens [1]
Aromatase (CYP19A1) DME Info Homo sapiens [3]
Cytochrome P450 2D6 (CYP2D6) DME Info Homo sapiens [1], [2]
Steroid 5-alpha-reductase 2 (SRD5A2) DME Info Homo sapiens [4]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [5]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [4]
Cytochrome P450 2B6 (CYP2B6) DME Info Homo sapiens [5]
References
1 Cr(VI) induces lipid peroxidation, protein oxidation and alters the activities of antioxidant enzymes in human erythrocytes. Biol Trace Elem Res. 2011 Dec;144(1-3):426-35.
2 3,4-Dihydroxybenzaldehyde quenches ROS and RNS and protects human blood cells from Cr(VI)-induced cytotoxicity and genotoxicity. Toxicol In Vitro. 2018 Aug;50:293-304.
3 Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro. Toxicol Appl Pharmacol. 2012 Jan 15;258(2):166-75.
4 Hexavalent chromium-induced alteration of proteomic landscape in human skin fibroblast cells. J Proteome Res. 2013 Jul 5;12(7):3511-8.
5 Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts. Toxicol Sci. 2008 Jun;103(2):325-34.

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