Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00995)
Xenobiotics Name
Amphibole asbestos
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Mixture
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Catalase (CAT) DME Info Homo sapiens [1]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [1]
Vitamin D(3) 24-hydroxylase (CYP24A1) DME Info Homo sapiens [2]
Dimethylaniline oxidase 1 (FMO1) DME Info Homo sapiens [1]
Cellular glutathione peroxidase (GPX1) DME Info Homo sapiens [1]
Nitric oxide synthase inducible (NOS2) DME Info Homo sapiens [1]
Prostaglandin G/H synthase 1 (COX-1) DME Info Homo sapiens [1]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [1]
UDP-glucuronosyltransferase 1A4 (UGT1A4) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Metallothionein-2A (MT2A) DME Info Homo sapiens [1]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [3]
References
1 Effect of size fractionation on the toxicity of amosite and Libby amphibole asbestos. Toxicol Sci. 2010 Dec;118(2):420-34.
2 Mechanisms of oxidative stress and alterations in gene expression by Libby six-mix in human mesothelial cells. Part Fibre Toxicol. 2010 Sep 11;7:26.
3 In vitro determinants of asbestos fiber toxicity: effect on the relative toxicity of Libby amphibole in primary human airway epithelial cells. Part Fibre Toxicol. 2014 Jan 8;11:2.

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