Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO00999)
Xenobiotics Name
Butyraldehyde
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
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3D MOL 2D MOL
PubChem CID
261
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Alcohol dehydrogenase class-V (ADH6) DME Info Homo sapiens [1]
Aldo-keto reductase 1C4 (AKR1C4) DME Info Homo sapiens [1]
Porphobilinogen synthase (ALAD) DME Info Homo sapiens [1]
Aldehyde dehydrogenase 2 (ALDH2) DME Info Homo sapiens [1]
Aldehyde dehydrogenase 7 (ALDH7) DME Info Homo sapiens [1]
Succinate-semialdehyde dehydrogenase (ALDH5A1) DME Info Homo sapiens [1]
Arsenite methyltransferase (AS3MT) DME Info Homo sapiens [1]
Beta,beta-carotene 15,15'-dioxygenase (BCO1) DME Info Homo sapiens [1]
Carboxylesterase 1 (CES1) DME Info Homo sapiens [1]
Cathepsin A (CTSA) DME Info Homo sapiens [1]
Cytochrome P450 2S1 (CYP2S1) DME Info Homo sapiens [1]
Leukotriene B4 omega-hydroxylase (CYP4F3) DME Info Homo sapiens [1]
Delta(24)-sterol reductase (DHCR24) DME Info Homo sapiens [1]
Short-chain dehydrogenase/reductase retSDR1 (DHRS3) DME Info Homo sapiens [1]
Dihydrothymine dehydrogenase (DPYD) DME Info Homo sapiens [1]
Fatty acid desaturase 2 (FADS2) DME Info Homo sapiens [1]
Glutathione S-transferase alpha-2 (GSTA2) DME Info Homo sapiens [1]
Histamine N-methyltransferase (HNMT) DME Info Homo sapiens [1]
Monoamine oxidase type B (MAO-B) DME Info Homo sapiens [1]
S-adenosylmethionine synthase 1 (MAT1A) DME Info Homo sapiens [1]
Methionine adenosyltransferase II beta (MAT2B) DME Info Homo sapiens [1]
Peptide methionine sulfoxide reductase (MSRA) DME Info Homo sapiens [1]
Methionine-R-sulfoxide reductase B2 (MSRB2) DME Info Homo sapiens [1]
Methylenetetrahydrofolate reductase (MTHFR) DME Info Homo sapiens [1]
Vitamin B12 methionine synthase (MTR) DME Info Homo sapiens [1]
Methionine synthase reductase (MTRR) DME Info Homo sapiens [1]
Phosphodiesterase 7B (PDE7B) DME Info Homo sapiens [1]
UDP-glucuronosyltransferase 2B15 (UGT2B15) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Alcohol dehydrogenase class-I alpha (ADH1A) DME Info Homo sapiens [1]
Arachidonate 5-lipoxygenase (ALOX5) DME Info Homo sapiens [1]
Aldehyde oxidase (AOX1) DME Info Homo sapiens [1]
Asparagine synthetase (ASNS) DME Info Homo sapiens [1]
Carbonic anhydrase II (CA2) DME Info Homo sapiens [1]
Choline O-acetyltransferase (CHAT) DME Info Homo sapiens [1]
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [2], [1]
Retinoic acid 4-hydroxylase 26A1 (CYP26A1) DME Info Homo sapiens [1]
Cytochrome P450 2C18 (CYP2C18) DME Info Homo sapiens [1]
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [1]
Cytochrome P450 2J2 (CYP2J2) DME Info Homo sapiens [1]
Galactose kinase (GALK1) DME Info Homo sapiens [1]
Hexosephosphate aminotransferase 2 (GFPT2) DME Info Homo sapiens [1]
L-glutamine amidohydrolase (GLS) DME Info Homo sapiens [1]
Glutathione S-transferase mu-1 (GSTM1) DME Info Homo sapiens [1]
Heparanase (HPSE) DME Info Homo sapiens [1]
Indoleamine 2,3-dioxygenase 1 (IDO1) DME Info Homo sapiens [1]
Nitric oxide synthase inducible (NOS2) DME Info Homo sapiens [1]
Phosphodiesterase 5A (PDE5A) DME Info Homo sapiens [1]
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1]
Uridine phosphorylase 1 (UPP1) DME Info Homo sapiens [1]
Xanthine dehydrogenase/oxidase (XDH) DME Info Homo sapiens [1]
References
1 Integrated analysis of microRNA and mRNA expression profiles highlights aldehyde-induced inflammatory responses in cells relevant for lung toxicity. Toxicology. 2015 Aug 6;334:111-21.
2 Transcriptome profile analysis of saturated aliphatic aldehydes reveals carbon number-specific molecules involved in pulmonary toxicity. Chem Res Toxicol. 2014 Aug 18;27(8):1362-70.

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