Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01047)
Xenobiotics Name
Decamethrin
Xenobiotics Type
Fungicide(s), Herbicide(s) or Insecticide(s)
Classification
Pesticide/Insecticide
Structure
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3D MOL 2D MOL
PubChem CID
40585
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 2B6 (CYP2B6) DME Info Homo sapiens [1]
Cytochrome P450 2D6 (CYP2D6) DME Info Homo sapiens [2]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [3]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [4]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [5]
Cytochrome P450 2A6 (CYP2A6) DME Info Homo sapiens [6]
Mephenytoin 4-hydroxylase (CYP2C19) DME Info Homo sapiens [6]
Cytochrome P450 2C8 (CYP2C8) DME Info Homo sapiens [6]
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [6]
References
1 The inhibition of major human hepatic cytochrome P450 enzymes by 18 pesticides: comparison of the N-in-one and single substrate approaches. Toxicol In Vitro. 2013 Aug;27(5):1584-8.
2 An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes. J Environ Sci Health B. 2009 Aug;44(6):553-63.
3 Inhibition of the human liver microsomal and human cytochrome P450 1A2 and 3A4 metabolism of estradiol by deployment-related and other chemicals. Drug Metab Dispos. 2006 Sep;34(9):1606-14.
4 Early changes in proteome levels upon acute deltamethrin exposure in mammalian skin system associated with its neoplastic transformation potential. J Toxicol Sci. 2013;38(4):629-42.
5 Pyrethroids: cytotoxicity and induction of CYP isoforms in human hepatocytes. Drug Metabol Drug Interact. 2008;23(3-4):211-36.
6 Characterization of human cytochrome P450 induction by pesticides. Toxicology. 2012 Mar 29;294(1):17-26.

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