Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01145)
Xenobiotics Name
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
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3D MOL 2D MOL
PubChem CID
5289501
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Transglutaminase K (TGM1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Aromatase (CYP19A1) DME Info Homo sapiens [2]
Retinoic acid 4-hydroxylase 26A1 (CYP26A1) DME Info Homo sapiens [3]
Transglutaminase H (TGM2) DME Info Homo sapiens [4]
References
1 Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells. Cell Growth Differ. 1996 Aug;7(8):997-1004.
2 Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology. 2006 Nov 10;228(1):98-108.
3 Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides. Toxicol Appl Pharmacol. 2005 Jan 1;202(1):38-49.
4 Retinoic acid receptors and tissue-transglutaminase mediate short-term effect of retinoic acid on migration and invasion of neuroblastoma SH-SY5Y cells. Oncogene. 2006 Jan 12;25(2):240-7.

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