General Information of Xenobiotics (ID: XEO01162)
Xenobiotics Name
ES-936
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Investigative Agent
Structure
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3D MOL 2D MOL
PubChem CID
4470790
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Quinone reductase 1 (NQO1) DME Info Homo sapiens [1], [2]
References
1 Dicoumarol relieves serum withdrawal-induced G0/1 blockade in HL-60 cells through a superoxide-dependent mechanism. Biochem Pharmacol. 2005 Jun 1;69(11):1613-25.
2 Role for NAD(P)H:quinone oxidoreductase 1 and manganese-dependent superoxide dismutase in 17-(allylamino)-17-demethoxygeldanamycin-induced heat shock protein 90 inhibition in pancreatic cancer cells. J Pharmacol Exp Ther. 2011 Mar;336(3):874-80.

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