Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01191)
Xenobiotics Name
Aloe-emodin
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=10207"></iframe>
3D MOL 2D MOL
PubChem CID
10207
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [1]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [1]
Cytochrome P450 1B1 (CYP1B1) DME Info Homo sapiens [1]
Unclear metabolic mechanism (DME-unclear) DME Info Streptococcus mutans [2]
Glutamate racemase (MurI) DME Info Streptococcus mutans [2]
N-acetyltransferase 1 (NAT1) DME Info Homo sapiens [3]
Sulfotransferase 1A1 (SULT1A1) DME Info Homo sapiens [1]
Sulfotransferase 1E1 (SULT1E1) DME Info Homo sapiens [1]
References
1 The natural anthraquinones from Rheum palmatum induced the metabolic disorder of melatonin by inhibiting human CYP and SULT enzymes. Toxicol Lett. 2016 Nov 16;262:27-38.
2 In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones. Antimicrob Agents Chemother. 2007 Apr;51(4):1541-4.
3 Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2). Melanoma Res. 2005 Dec;15(6):489-94.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.