Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01228)
Xenobiotics Name
Brucine
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Acute Toxic Substance
Structure
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3D MOL 2D MOL
PubChem CID
442021
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Prostaglandin G/H synthase 2 (COX-2) DME Info Homo sapiens [1], [2]
References
1 The anti-tumor effects of alkaloids from the seeds of Strychnos nux-vomica on HepG2 cells and its possible mechanism. J Ethnopharmacol. 2006 Jun 30;106(2):179-86.
2 The cytotoxicity induced by brucine from the seed of Strychnos nux-vomica proceeds via apoptosis and is mediated by cyclooxygenase 2 and caspase 3 in SMMC 7221 cells. Food Chem Toxicol. 2007 Sep;45(9):1700-8.

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