Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01245)
Xenobiotics Name
Chlordan
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
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3D MOL 2D MOL
PubChem CID
5993
DME(s) Modulated by This Xenobiotics
DME(s) Induced by This Xenobiotics
Aromatase (CYP19A1) DME Info Homo sapiens [1]
Retinoic acid 4-hydroxylase 26A1 (CYP26A1) DME Info Homo sapiens [2]
Cytochrome P450 2B6 (CYP2B6) DME Info Homo sapiens [3]
Cytochrome P450 3A4 (CYP3A4) DME Info Homo sapiens [3]
References
1 Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology. 2006 Nov 10;228(1):98-108.
2 Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides. Toxicol Appl Pharmacol. 2005 Jan 1;202(1):38-49.
3 A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides. Biochem Pharmacol. 2004 Dec 15;68(12):2347-58.

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