Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01370)
Xenobiotics Name
Mangiferin
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
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3D MOL 2D MOL
PubChem CID
5281647
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 2C9 (CYP2C9) DME Info Homo sapiens [1]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Catalase (CAT) DME Info Homo sapiens [2]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [3]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DME Info Homo sapiens [4]
References
1 Brazil nut improves the oxidative metabolism of superoxide-hydrogen peroxide chemically-imbalanced human fibroblasts in a nutrigenomic manner. Food Chem Toxicol. 2018 Nov;121:519-526.
2 Mangifera indica Lextract and mangiferin modulate cytochrome P450 and UDP-glucuronosyltransferase enzymes in primary cultures of human hepatocytes. Phytother Res. 2013 May;27(5):745-52.
3 The role S-nitrosylation in manganese-induced autophagy dysregulation in SH-SY5Y cells. Environ Toxicol. 2017 Dec;32(12):2428-2439.
4 Gene expression profiling of human primary astrocytes exposed to manganese chloride indicates selective effects on several functions of the cells. Neurotoxicology. 2007 May;28(3):478-89.

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