Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01448)
Xenobiotics Name
Pyruvaldehyde
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
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3D MOL 2D MOL
PubChem CID
880
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Serum paraoxonase/arylesterase 1 (PON1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Succinic semialdehyde reductase (AKR7A2) DME Info Homo sapiens [2]
Quinone reductase 1 (NQO1) DME Info Homo sapiens [3]
References
1 StJohn's wort extracts and some of their constituents potently inhibit ultimate carcinogen formation from benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1. Cancer Res. 2003 Nov 15;63(22):8062-8.
2 Anti-tumor properties of methoxylated analogues of resveratrol in malignant MCF-7 but not in non-tumorigenic MCF-10A mammary epithelial cell lines. Toxicology. 2019 Jun 15;422:35-43.
3 Protopine and allocryptopine increase mRNA levels of cytochromes P450 1A in human hepatocytes and HepG2 cells independently of AhR. Toxicol Lett. 2011 Jun 10;203(2):135-41.

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