Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01504)
Xenobiotics Name
Gold
Xenobiotics Type
Other Chemical Compound(s) or Element(s)
Classification
Chemical Compound
Structure
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3D MOL 2D MOL
PubChem CID
23985
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Alcohol dehydrogenase class-III (ADH5) DME Info Homo sapiens [1]
Hypoxanthine phosphoribosyltransferase (HPRT1) DME Info Homo sapiens [1]
Tryptophan oxygenase (TRPO) DME Info Homo sapiens [1]
Thioredoxin reductase TR1 (TXNRD1) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Small intestine reductase (AKR1B10) DME Info Homo sapiens [3]
Aldo-keto reductase 1C2 (AKR1C2) DME Info Homo sapiens [3]
Aldo-keto reductase 1C3 (AKR1C3) DME Info Homo sapiens [3]
Vitamin D(3) 24-hydroxylase (CYP24A1) DME Info Homo sapiens [3]
Metallothionein-2A (MT2A) DME Info Homo sapiens [1]
Nitric oxide synthase inducible (NOS2) DME Info Homo sapiens [4]
Quinone reductase 1 (NQO1) DME Info Homo sapiens [3]
Prostaglandin reductase 1 (PTGR1) DME Info Homo sapiens [3]
References
1 Changes in Caco-2 cells transcriptome profiles upon exposure to gold nanoparticles. Toxicol Lett. 2015 Mar 4;233(2):187-99.
2 Noble metal targeting of thioredoxin reductase--covalent complexes with thioredoxin and thioredoxin-related protein of 14 kDa triggered by cisplatin. Free Radic Biol Med. 2010 Dec 1;49(11):1765-78.
3 Gold nanoparticles induce serum amyloid A 1-Toll-like receptor 2 mediated NF-kB signaling in lung cells in vitro. Chem Biol Interact. 2018 Jun 1;289:81-89.
4 Effects of gold and silver nanoparticles in cultured human osteoarthritic chondrocytes. J Appl Toxicol. 2013 Dec;33(12):1506-13.

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