Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01506)
Xenobiotics Name
Lead chloride
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Health Hazard/Toxicant
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=24459"></iframe>
3D MOL 2D MOL
PubChem CID
24459
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Glutathione S-transferase mu-1 (GSTM1) DME Info Homo sapiens [1]
Nitric oxide synthase brain (NOS1) DME Info Homo sapiens [2]
Nitric oxide synthase inducible (NOS2) DME Info Homo sapiens [2]
Nitric oxide synthase endothelial (NOS3) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Small intestine reductase (AKR1B10) DME Info Homo sapiens [3]
Aldo-keto reductase 1C1 (AKR1C1) DME Info Homo sapiens [3]
Aldo-keto reductase 1C2 (AKR1C2) DME Info Homo sapiens [3]
References
1 Circulatory heavy metals (cadmium, lead, mercury, and chromium) inversely correlate with plasma GST activity and GSH level in COPD patients and impair NOX4/Nrf2/GCLC/GST signaling pathway in cultured monocytes. Toxicol In Vitro. 2019 Feb;54:269-279.
2 The cytotoxic effect of the NOS-mediated oxidative stress in MCF-7 cells after PbCl?exposure. Environ Toxicol. 2016 May;31(5):601-8.
3 Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors. Arch Toxicol. 2008 Aug;82(8):513-24.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.