Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01509)
Xenobiotics Name
Mercury
Xenobiotics Type
Health or Environmental Toxicant(s)
Classification
Acute Toxic Substance
Structure
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3D MOL 2D MOL
PubChem CID
23931
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Neprilysin (MME) DME Info Homo sapiens [1]
Serum paraoxonase/arylesterase 1 (PON1) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Acetylcholinesterase (ACHE) DME Info Homo sapiens [3]
Cellular glutathione peroxidase (GPX1) DME Info Homo sapiens [3]
Thymidylate synthase (TYMS) DME Info Homo sapiens [3]
References
1 Polycyclic aromatic hydrocarbon/metal mixtures: effect on PAH induction of CYP1A1 in human HEPG2 cells. Drug Metab Dispos. 2001 Jul;29(7):999-1006.
2 Mechanisms of cholinesterase inhibition by inorganic mercury. FEBS J. 2007 Apr;274(7):1849-61.
3 A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 2015 Sep;89(9):1599-618.

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