Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO02228)
Xenobiotics Name
Aniline
Xenobiotics Type
Other Chemical Compound(s) or Element(s)
Classification
Chemical Compound
Structure
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3D MOL 2D MOL
PubChem CID
6115
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aromatase (CYP19A1) DME Info Homo sapiens [1]
Cytochrome P450 2E1 (CYP2E1) DME Info Homo sapiens [2], [3]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [4]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [4]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [4]
References
1 Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition. J Med Chem. 2006 Feb 23;49(4):1413-9.
2 Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat. Drug Metab Dispos. 2003 Jul;31(7):833-6.
3 Drug-drug interactions of Z-338, a novel gastroprokinetic agent, with terfenadine, comparison with cisapride, and involvement of UGT1A9 and 1A8 in the human metabolism of Z-338. Eur J Pharmacol. 2004 Aug 23;497(2):223-31.
4 Synthesis and anti-biofilm activities of dihydro-pyrrol-2-one derivatives on Pseudomonas aeruginosa. Bioorg Med Chem Lett. 2015 Feb 1;25(3):597-601.

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