Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO02850)
Xenobiotics Name	Circulin-A
Xenobiotics Type	Amino Acid(s), Peptide(s) or Protein(s)
Classification	Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
DME(s) Inhibited by This Xenobiotics	NADPH-dependent oxidoreductase (nfrA)	DME Info	Staphylococcus aureus	[1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data	NADPH-dependent oxidoreductase (nfrA)	DME Info	MIC = 0.19 microM	[1], [2]

References
1	An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):8913-8.
2	Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity. J Mol Biol. 1999 Jan 8;285(1):333-45.

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