Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO04334) | ||||||
|---|---|---|---|---|---|---|
| Xenobiotics Name |
Novispirin T-7
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| Xenobiotics Type |
Amino Acid(s), Peptide(s) or Protein(s)
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| Classification |
Peptide
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| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Glutamate decarboxylase (gadB) | DME Info | Listeria monocytogenes | [1] | |||
| D-Lactate dehydrogenase (ldhA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | Pseudomonas aeruginosa | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | Staphylococcus aureus | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | Pseudomonas aeruginosa | [1] | |||
| Xenobiotics-DME Activity Data | ||||||
| Xenobiotics-DME Activity Data | Glutamate decarboxylase (gadB) | DME Info | MIC = 2.4 ug/ml | [1] | ||
| D-Lactate dehydrogenase (ldhA) | DME Info | MIC = 0.26-27.8 ug/ml | [1] | |||
| Arylamine N-acetyltransferase (NAT) | DME Info | MIC = 0.26-27.8 ug/ml | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | MIC = 3.3 ug/ml | [1] | |||
| Hydroxybenzoate 3-monooxygenase (pobA) | DME Info | MIC = 0.26-27.8 ug/ml | [1] | |||
| References | ||||||
| 1 | Impact of single-residue mutations on the structure and function of ovispirin/novispirin antimicrobial peptides. Protein Eng. 2002 Mar;15(3):225-32. | |||||
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