Detail Information of Xenobiotics
| General Information of Xenobiotics (ID: XEO04560) | ||||||
|---|---|---|---|---|---|---|
| Xenobiotics Name |
Phlebotomus duboscqi defensin
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| Xenobiotics Type |
Amino Acid(s), Peptide(s) or Protein(s)
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| Classification |
Peptide
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| DME(s) Modulated by This Xenobiotics | ||||||
| DME(s) Inhibited by This Xenobiotics | ||||||
| Cytochrome P450 monooxygenase 51A (cyp51A) | DME Info | Aspergillus fumigatus | [1] | |||
| Unclear metabolic mechanism (DME-unclear) | DME Info | Saccharomyces cerevisiae | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | Staphylococcus aureus | [1] | |||
| Xenobiotics-DME Activity Data | ||||||
| Xenobiotics-DME Activity Data | Cytochrome P450 monooxygenase 51A (cyp51A) | DME Info | MIC = 12.5-25 microM | [1] | ||
| Unclear metabolic mechanism (DME-unclear) | DME Info | MIC = 25-50 microM | [1] | |||
| NADPH-dependent oxidoreductase (nfrA) | DME Info | MIC = 0.78-1.56 microM | [1] | |||
| References | ||||||
| 1 | Characterization of a defensin from the sand fly Phlebotomus duboscqi induced by challenge with bacteria or the protozoan parasite Leishmania major. Infect Immun. 2004 Dec;72(12):7140-6. | |||||
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