Drug Information

Drug General Information
Drug ID
D0B1MU
Former ID
DNC002511
Drug Name
Compound 15
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Formula
C28H31NO4S
Canonical SMILES
CC1CN(CC1C)CCOC2=CC=C(C=C2)C3C(SC4=C(O3)C=CC(=C4)O)C5=C<br />C=C(C=C5)O
InChI
1S/C28H31NO4S/c1-18-16-29(17-19(18)2)13-14-32-24-10-5-20(6-11-24)27-28(21-3-7-22(30)8-4-21)34-26-15-23(31)9-12-25(26)33-27/h3-12,15,18-19,27-28,30-31H,13-14,16-17H2,1-2H3/t18-,19-,27-,28-/m0/s1
InChIKey
COJFASLRENZFLP-HVYZTVOGSA-N
PubChem Compound ID
46936266
PubChem Substance ID
46504441, 46507663, 137002192, 162103326, 247384803
Target and Pathway
Target(s) Estrogen receptor Target Info Inhibitor [551393]
mRNA of Protein tyrosine phosphatase-1B Target Info Inhibitor [551393]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Proteoglycans in cancerhsa04520:Adherens junction
Insulin signaling pathway
NetPath Pathway FSH Signaling Pathway
EGFR1 Signaling Pathway
RANKL Signaling PathwayNetPath_25:FSH Signaling Pathway
PANTHER Pathway Cadherin signaling pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Signaling events mediated by HDAC Class II
Plasma membrane estrogen receptor signaling
LKB1 signaling events
Regulation of Telomerase
ATF-2 transcription factor network
AP-1 transcription factor network
FOXM1 transcription factor network
Validated nuclear estrogen receptor alpha network
Signaling mediated by p38-alpha and p38-beta
FOXA1 transcription factor networkinsulin_pathway:Insulin Pathway
Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
Signaling events mediated by PTP1B
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Signaling events mediated by TCPTP
IGF1 pathway
EGF receptor (ErbB1) signaling pathway
Posttranslational regulation of adherens junction stability and dissassembly
PDGFR-beta signaling pathway
N-cadherin signaling events
Reactome Nuclear signaling by ERBB4
Nuclear Receptor transcription pathwayR-HSA-354192:Integrin alphaIIb beta3 signaling
Regulation of IFNG signaling
Regulation of IFNA signaling
Growth hormone receptor signaling
WikiPathways Estrogen signaling pathway
Nuclear Receptors Meta-Pathway
Estrogen Receptor Pathway
Signaling by ERBB4
JAK/STAT
Integrated Pancreatic Cancer Pathway
Leptin signaling pathway
miR-targeted genes in muscle cell - TarBase
Integrated Breast Cancer Pathway
Nuclear ReceptorsWP481:Insulin Signaling
Growth hormone receptor signaling
Interferon gamma signaling
Interferon alpha/beta signaling
Integrin alphaIIb beta3 signaling
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.