Target General Information
Target ID	T73992
Target Name	Beta-secretase
Synonyms	BACE1; ASP2; Aspartyl protease 2; BACE; Beta-site AbetaPP-cleaving enzyme; Beta-site amyloid precursor protein cleaving enzyme; Memapsin-2; Membrane-associated aspartic protease 2; Transmembrane aspartic protease
Target Type	Clinical Trial
Gene Name	BACE1
Biochemical Class	Peptidase
UniProt ID	BACE1_HUMAN||BACE2_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 532395	AZ-4217: a high potency BACE inhibitor displaying acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. J Neurosci. 2013 Jun 12;33(24):10075-84.
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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