Target General Information
Target ID T76904
Target Name Catechol-O-methyl-transferase
Synonyms Catechol-O-methyltransferase; MB-COMT; S-COMT; COMT
Target Type Successful
Gene Name COMT
Biochemical Class Methyltransferase superfamily
UniProt ID COMT_HUMAN
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 548315Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024498)
Ref 541757(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6647).
Ref 536923Drugs used to treat Parkinson's disease, present status and future directions. CNS Neurol Disord Drug Targets. 2008 Oct;7(4):321-42.
Ref 530430CGP 28014, a new inhibitor of cerebral catechol-O-methylation with a non-catechol structure. Naunyn Schmiedebergs Arch Pharmacol. 1990 Sep;342(3):305-11.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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