Details of Host Protein-DME Interaction (HOSPPI)
| General Information of Drug-Metabolizing Enzyme (DME ID: DME1106) | |||||
|---|---|---|---|---|---|
| DME Name | Arylamine N-acetyltransferase (NAT), Klebsiella pneumoniae | DME Info | |||
| UniProt ID | |||||
| EC Number | EC: 2.3.1.5 (Click to Show/Hide the Complete EC Tree) | ||||
| Lineage | Species: Klebsiella pneumoniae (Click to Show/Hide the Complete Species Lineage) | ||||
| Interactome | |||||
| Disease Specific Interactions between Host Protein and DME (HOSPPI) | |||||
|---|---|---|---|---|---|
| Drug co-metabolism | |||||
| Cometabolized drug: Asacolitin | Click to Show/Hide the Full List of HOSPPI: 2 HOSPPI | ||||
| N-acetyltransferase 1 (NAT1) | Click to Show/Hide the Cometabolization Info | ||||
| DME ID | DME0050 DME Info | ||||
| Uniprot ID | |||||
| Interaction Name | NAT1-NAT interaction | [1], [1] | |||
| Description | The interaction, between human N-acetyltransferase 1 and Arylamine N-acetyltransferase from Klebsiella pneumoniae which collectively metabolize the drug Asacolitin, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. | ||||
| N-acetyltransferase 2 (NAT2) | Click to Show/Hide the Cometabolization Info | ||||
| DME ID | DME0051 DME Info | ||||
| Uniprot ID | |||||
| Interaction Name | NAT2-NAT interaction | [1], [1] | |||
| Description | The interaction, between human N-acetyltransferase 2 and Arylamine N-acetyltransferase from Klebsiella pneumoniae which collectively metabolize the drug Asacolitin, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. | ||||
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