| Disease Specific Interactions between Host Protein and DME (HOSPPI) |
| Drug co-metabolism |
| Cometabolized drug: RO-7-0207 |
Click to Show/Hide the Full List of HOSPPI: 3 HOSPPI
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| Cytochrome P450 3A4 (CYP3A4) |
Click to Show/Hide the Cometabolization Info |
| DME ID |
DME0001
DME Info
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| Uniprot ID |
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| Interaction Name |
CYP3A4-fadd interaction |
[1], [2] |
| Description |
The interaction, between human Cytochrome P450 3A4 and Flavin adenine dinucleotide dehydrogenase from Eubacterium oxidoreducens which collectively metabolize the drug RO-7-0207, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
| Cytochrome P450 3A5 (CYP3A5) |
Click to Show/Hide the Cometabolization Info |
| DME ID |
DME0012
DME Info
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| Uniprot ID |
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| Interaction Name |
CYP3A5-fadd interaction |
[1], [2] |
| Description |
The interaction, between human Cytochrome P450 3A5 and Flavin adenine dinucleotide dehydrogenase from Eubacterium oxidoreducens which collectively metabolize the drug RO-7-0207, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
| Cytochrome P450 3A7 (CYP3A7) |
Click to Show/Hide the Cometabolization Info |
| DME ID |
DME0015
DME Info
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| Uniprot ID |
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| Interaction Name |
CYP3A7-fadd interaction |
[1], [2] |
| Description |
The interaction, between human Cytochrome P450 3A7 and Flavin adenine dinucleotide dehydrogenase from Eubacterium oxidoreducens which collectively metabolize the drug RO-7-0207, is reported to affect the efficacy, safety or bioavailability of this drug via interfering with it metabolism. |
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