Details of Microbiome-DME Interaction (MICBIO)

General Information of Drug-Metabolizing Enzyme (DME ID: DME0011)
DME Name Glutathione S-transferase alpha-1 (GSTA1), Homo sapiens DME Info
UniProt ID
GSTA1_HUMAN
EC Number    EC: 2.5.1.18     (Click to Show/Hide the Complete EC Tree)
Transferase
Alkyl/aryl transferase
Alkyl/aryl transferase
EC: 2.5.1.18
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
Interactome
Interactions between Microbiome and DME (MICBIO)
      Bacteria: Actinobacteria
                  Bifidobacterium adolescentis (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bifidobacterium adolescentis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bifidobacterium adolescentis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bifidobacterium breve (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bifidobacterium breve co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bifidobacterium breve co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bifidobacterium longum (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bifidobacterium longum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bifidobacterium longum co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bifidobacterium ruminatum (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bifidobacterium ruminatum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bifidobacterium ruminatum co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Collinsella intestinalis (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Collinsella intestinalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Collinsella intestinalis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Eggerthella lenta (actinobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Eggerthella lenta co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Eggerthella lenta co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Bacteroidetes
                  Alistipes indistinctus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Alistipes indistinctus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Alistipes indistinctus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides cellulosilyticus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides cellulosilyticus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides cellulosilyticus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides coprophilus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides coprophilus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides dorei (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides dorei co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides dorei co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides dorei co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Bacteroides eggerthii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides eggerthii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides eggerthii co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides finegoldii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides finegoldii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides finegoldii co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides fragilis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides fragilis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides fragilis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides intestinalis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides intestinalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides intestinalis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides ovatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides ovatus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides ovatus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides sartorii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides sartorii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides sartorii co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides sartorii co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Bacteroides stercoris (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides stercoris co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides stercoris co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides thetaiotaomicron (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides thetaiotaomicron co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides thetaiotaomicron co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides uniformis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides uniformis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides uniformis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacteroides vulgatus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides vulgatus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides vulgatus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides vulgatus co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Bacteroides xylanisolvens (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides xylanisolvens co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides xylanisolvens co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides xylanisolvens co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Odoribacter splanchnicus (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Odoribacter splanchnicus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Odoribacter splanchnicus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Parabacteroides distasonis (CFB bacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Parabacteroides distasonis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Parabacteroides distasonis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                              Phenytoin Click to Show/Hide the Detail
                                 Drug ID DR1282   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Parabacteroides distasonis co-metabolize the drug Phenytoin, which can collectively affect efficacy, safety or bioavailability of this drug. [4], [2]
                  Parabacteroides johnsonii (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Parabacteroides johnsonii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Parabacteroides johnsonii co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Parabacteroides merdae (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Parabacteroides merdae co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Parabacteroides merdae co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Prevotella copri (CFB bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Prevotella copri co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Prevotella copri co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Firmicutes
                  Anaerobutyricum hallii (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Anaerobutyricum hallii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Anaerobutyricum hallii co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Anaerococcus hydrogenalis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Anaerococcus hydrogenalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Anaerococcus hydrogenalis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Anaerostipes hadrus (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Anaerostipes hadrus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Anaerostipes hadrus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Anaerotruncus colihominis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Anaerotruncus colihominis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Anaerotruncus colihominis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Bacillus megaterium (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacillus megaterium co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [6]
                              Progesterone Click to Show/Hide the Detail
                                 Drug ID DR1346   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacillus megaterium co-metabolize the drug Progesterone, which can collectively affect efficacy, safety or bioavailability of this drug. [7], [8]
                  Bacteroides pectinophilus (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides pectinophilus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Bacteroides pectinophilus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Blautia hansenii (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Blautia hansenii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Blautia hansenii co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Blautia luti (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Blautia luti co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Blautia luti co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridioides difficile (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridioides difficile co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [9]
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridioides difficile co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridioides difficile co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium botulinum (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium botulinum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium botulinum co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium scindens (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium scindens co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium scindens co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium spiroforme (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium spiroforme co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium spiroforme co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium sporogenes (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium sporogenes co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium sporogenes co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Clostridium symbiosum (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium symbiosum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Clostridium symbiosum co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Coprococcus comes (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Coprococcus comes co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Coprococcus comes co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Dorea formicigenerans (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Dorea formicigenerans co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Dorea formicigenerans co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterocloster asparagiformis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterocloster asparagiformis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterocloster asparagiformis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterocloster bolteae (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterocloster bolteae co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterocloster bolteae co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterococcus faecalis (firmicutes) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterococcus faecalis co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [9]
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterococcus faecalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterococcus faecalis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Erysipelatoclostridium ramosum (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Erysipelatoclostridium ramosum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Erysipelatoclostridium ramosum co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Eubacterium rectale (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Eubacterium rectale co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Eubacterium rectale co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Eubacterium ventriosum (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Eubacterium ventriosum co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Eubacterium ventriosum co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Holdemanella biformis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Holdemanella biformis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Holdemanella biformis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Hungatella hathewayi (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Hungatella hathewayi co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Hungatella hathewayi co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Lactobacillus reuteri (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Lactobacillus reuteri co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Lactobacillus reuteri co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Marvinbryantia formatexigens (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Marvinbryantia formatexigens co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Marvinbryantia formatexigens co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Roseburia intestinalis (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Roseburia intestinalis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Roseburia intestinalis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Ruminococcus gnavus (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Ruminococcus gnavus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Ruminococcus gnavus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Ruminococcus lactaris (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Ruminococcus lactaris co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Ruminococcus lactaris co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Ruminococcus torques (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Ruminococcus torques co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Ruminococcus torques co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Subdoligranulum variabile (firmicutes) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Subdoligranulum variabile co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Subdoligranulum variabile co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Lentisphaerae
                  Victivallis vadensis (PVC bacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Victivallis vadensis co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Victivallis vadensis co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Proteobacteria
                  Citrobacter freundii (enterobacteria) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Citrobacter freundii co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [9]
                  Edwardsiella tarda (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Edwardsiella tarda co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Edwardsiella tarda co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Enterobacter cancerogenus (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterobacter cancerogenus co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Enterobacter cancerogenus co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Escherichia coli (enterobacteria) Click to Show/Hide the Full List of Drugs:        3 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Escherichia coli co-metabolize the drug Acetaminophen, which can collectively affect efficacy, safety or bioavailability of this drug. [5], [9]
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Escherichia coli co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Escherichia coli co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Proteus penneri (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Proteus penneri co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Proteus penneri co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Providencia alcalifaciens (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Providencia alcalifaciens co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Providencia alcalifaciens co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Providencia rettgeri (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Providencia rettgeri co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Providencia rettgeri co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Providencia stuartii (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Providencia stuartii co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Providencia stuartii co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
                  Salmonella enterica (enterobacteria) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Salmonella enterica co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Salmonella enterica co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Bacteria: Verrucomicrobia
                  Akkermansia muciniphila (verrucomicrobiae) Click to Show/Hide the Full List of Drugs:        2 Drugs Metabolized
                              Artemisinin Click to Show/Hide the Detail
                                 Drug ID DR0141   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Akkermansia muciniphila co-metabolize the drug Artemisinin, which can collectively affect efficacy, safety or bioavailability of this drug. [1], [2]
                              Melphalan Click to Show/Hide the Detail
                                 Drug ID DR1021   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) and Akkermansia muciniphila co-metabolize the drug Melphalan, which can collectively affect efficacy, safety or bioavailability of this drug. [3], [2]
      Fungi: Ascomycota
                  Saccharomyces cerevisiae (ascomycota) Click to Show/Hide the Full List of Drugs:        1 Drugs Metabolized
                              Acetaminophen Click to Show/Hide the Detail
                                 Drug ID DR0037   Drug Info
                                 Interaction Mechanism Human Glutathione S-transferase alpha-1 (GSTA1) metabolizes the drug Acetaminophen, and Saccharomyces cerevisiae further metabolizes its metabolite (1-Phenyl-1,2-propanedione), which can indirectly affect efficacy, safety or bioavailability of this drug. [5], [9]
References
1 Inhibition of glutathione S-transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance. Int J Cancer. 2002 Feb 10;97(5):700-5.
2 Mapping human microbiome drug metabolism by gut bacteria and their genes. Nature. 2019 Jun;570(7762):462-467.
3 Metabolism of melphalan by rat liver microsomal glutathione S-transferase. Chem Biol Interact. 2005 Apr 15;152(2-3):101-6.
4 Comparison of basal glutathione S-transferase activities and of the influence of phenobarbital, butylated hydroxy-anisole or 5,5'-diphenylhydantoin on enzyme activity in male rodents. Comp Biochem Physiol C. 1987;88(1):91-3.
5 Retinoid X receptor alpha regulates the expression of glutathione s-transferase genes and modulates acetaminophen-glutathione conjugation in mouse liver. Mol Pharmacol. 2005 Dec;68(6):1590-6.
6 The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities. Trends Biotechnol. 2007 Jul;25(7):289-98.
7 Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones. J Biol Chem. 2001 Aug 31;276(35):33061-5.
8 acillus megaterium SF185 spores exert protective effects against oxidative stress in vivo and in vitro. Sci Rep. 2019 Aug 19;9(1):12082.
9 Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice. J Hepatol. 2018 Jul;69(1):51-59.

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