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Progesterone was approved by FDA. The 2020 official website of the U.S. Food and Drug Administration.
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DrugBank(Pharmacology-Metabolism)Progesterone
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Human cytochrome P450 21A2, the major steroid 21-hydroxylase: structure of the enzyme progesterone substrate complex and rate-limiting C-H bond cleavage. J Biol Chem. 2015 May 22;290(21):13128-43.
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Progesterone Metabolites Produced by Cytochrome P450 3A Modulate Uterine Contractility in a Murine Model Reprod Sci. 2015 Dec;22(12):1577-86. doi: 10.1177/1933719115589414.
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FDA:Progesterone
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