| General Information of DME (ID: DME0148) |
| DME Name |
Pancreatic alpha-amylase (AMY2A), Homo sapiens
|
| Synonyms |
Alpha-D-glucan glucanohydrolase; 1,4-alpha-D-glucan glucanohydrolase; AMY2A; PA
|
| Gene Name |
AMY2A
|
| UniProt ID |
|
| Gene ID |
|
| EC Number |
EC: 3.2.1.1 (Click to Show/Hide the Complete EC Tree)
Hydrolases
Glycosylase
O/S-glycosyl compound glycosidase
EC: 3.2.1.1
|
| Lineage |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
|
Interactome(loading-time for this interactome depdends on the speed of web connection)
|
Interactions between Xenobiotics and DME (XEOTIC)  Jump to Detailed Interactome Data  |
|
|
|
Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
|
| Sequence |
MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPP
NENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGN
AVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGL
LDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAG
SKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWG
FVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWP
RQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQP
FTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGI
KIYVSDDGKAHFSISNSAEDPFIAIHAESKL
|
| Structure |
1CPU
; 1HNY
; 1KB3
; 1KBB
; 1KBK
; 1KGU
; 1KGW
; 1KGX
; 1U2Y
|
| Pathway |
Carbohydrate digestion and absorption (hsa04973 ) |
| Metabolic pathways (hsa01100 ) |
| Pancreatic secretion (hsa04972 ) |
| Starch and sucrose metabolism (hsa00500 ) |
| Function |
This enzyme hydrolyzes 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen.
|
|
|
|
|
|
|
