| General Information of DME (ID: DME0407) |
| DME Name |
Aquaporin adipose (AQP7), Homo sapiens
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| Synonyms |
Aquaglyceroporin-7; Aquaporin-7; Aquaporin-7-like; AQP-7; AQP7; AQP7L; AQP9; AQPap
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| Gene Name |
AQP7
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| UniProt ID |
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| Gene ID |
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| EC Number |
EC: 3.1.1.- (Click to Show/Hide the Complete EC Tree)
Hydrolases
Ester bond hydrolase
Carboxylic ester hydrolase
EC: 3.1.1.-
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| Lineage |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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Interactome(loading-time for this interactome depdends on the speed of web connection)
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Interactions between Microbiome and DME (MICBIO)  Jump to Detailed Interactome Data  |
Interactions between Xenobiotics and DME (XEOTIC)  Jump to Detailed Interactome Data |
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Sequence |
MVQASGHRRSTRGSKMVSWSVIAKIQEILQRKMVREFLAEFMSTYVMMVFGLGSVAHMVL
NKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQF
LGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTG
MLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIA
GWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITV
LPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
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| Structure |
6KXW
; 6N1G
; 6QZI
; 6QZJ
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| Pathway |
PPAR signaling pathway (hsa03320 ) |
| Regulation of lipolysis in adipocytes (hsa04923 ) |
| Function |
This enzyme functions as important facilitator of glycerol transport across the cell membrane and modulators in controlling the metabolism of glycerol, contributing to the pathophysiology of obesity and diabetes.
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