Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1272)
DME Name Unclear metabolic mechanism (DME-unclear), Gardnerella vaginalis
Gene Name DME-unclear
Lineage    Species: Gardnerella vaginalis     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Gardnerella
Species: Gardnerella vaginalis
Interactome
(loading-time for this interactome depdends on the speed of web connection)
       Interactions between Xenobiotics and DME (XEOTIC)                      
Jump to Detailed Interactome Data                      
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human gut, vagina and urogenital tract.
Full List of Drug(s) Metabolized by This DME
      Drugs Approved by FDA Click to Show/Hide the Full List of Drugs:          1 Drugs
Tenofovir alafenamide
 Drug Info Approved Viral hepatitis ICD11: 1E51 [1], [2]
References
1 Vaginal microbiome modulates topical antiretroviral drug pharmacokinetics. JCI Insight. 2018 Jul 12;3(13). pii: 99545.
2 Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women. Science. 2017 Jun 2;356(6341):938-945.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.