Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1288)
DME Name Unclear metabolic mechanism (DME-unclear), Shewanella oneidensis
Gene Name DME-unclear
Lineage    Species: Shewanella oneidensis     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Alteromonadales
Family: Shewanellaceae
Genus: Shewanella
Species: Shewanella oneidensis
Subspecies: Shewanella oneidensis MR-1
Interactome
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       Interactions between Xenobiotics and DME (XEOTIC)                      
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      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human gut.
Full List of Drug(s) Metabolized by This DME
      Drugs Approved by FDA Click to Show/Hide the Full List of Drugs:          3 Drugs
Sulfamethoxazole
 Drug Info Approved Infectious cystitis ICD11: GC00 [1], [2]
Sulfapyridine
 Drug Info Approved Dermatitis herpetiformis ICD11: EB44 [1], [2]
Sulfacetamide
 Drug Info Approved Seborrhoeic dermatitis ICD11: EA81 [1]
References
1 Biodegradation of sulfonamides by Shewanella oneidensis MR-1 and Shewanella sp. strain MR-4. Biodegradation. 2018 Apr;29(2):129-140.
2 The 285 kDa Bap/RTX hybrid cell surface protein (SO4317) of Shewanella oneidensis MR-1 is a key mediator of biofilm formation. Res Microbiol. 2010 Mar;161(2):144-52.

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