General Information of DME (ID: DME1363)
DME Name Unclear metabolic mechanism (DME-unclear), Bacteroides cellulosilyticus
Gene Name DME-unclear
Lineage    Species: Bacteroides cellulosilyticus     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Bacteroidaceae
Genus: Bacteroides
Species: Bacteroides cellulosilyticus
Subspecies: Bacteroides cellulosilyticus DSM 14838
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human gut.
Full List of Drug(s) Metabolized by This DME
      Drugs Approved by FDA Click to Show/Hide the Full List of Drugs:        26 Drugs
Terbinafine hydrochloride
Drug Info Approved Pityriasis versicolor ICD11: 1F2D [1]
Deflazacort
Drug Info Approved Muscular dystrophy ICD11: 8C70 [1]
Levonorgestrel
Drug Info Approved Menorrhagia ICD11: GA20 [1]
Norethindrone acetate
Drug Info Approved Menorrhagia ICD11: GA20 [1]
Danazol
Drug Info Approved Endometriosis ICD11: GA10 [1]
Famciclovir
Drug Info Approved Genital herpes ICD11: 1A94 [1]
Omeprazole
Drug Info Approved Gastro-oesophageal reflux disease ICD11: DA22 [1]
Ramipril
Drug Info Approved Essential hypertension ICD11: BA00 [1]
Sulfasalazine
Drug Info Approved Rheumatoid arthritis ICD11: FA20 [1]
Tolazamide
Drug Info Approved Diabetes mellitus ICD11: 5A10 [1]
Vilazodone hydrochloride
Drug Info Approved Depression ICD11: 6A71 [1]
Clemastine fumarate
Drug Info Approved Pulmonary oedema ICD11: CB01 [1]
Lovastatin
Drug Info Approved Hypertriglyceridaemia ICD11: 5C80 [1]
Pantoprazole sodium
Drug Info Approved Gastro-oesophageal reflux disease ICD11: DA22 [1]
Bromocriptine mesylate
Drug Info Approved Parkinsonism ICD11: 8A00 [1]
Carisoprodol
Drug Info Approved Depression ICD11: 6A71 [1]
Entacapone
Drug Info Approved Parkinsonism ICD11: 8A00 [1]
Mebendazole
Drug Info Approved Ascariasis ICD11: 1F62 [1]
Melphalan
Drug Info Approved Multiple myeloma ICD11: 2A83 [1]
Quinapril
Drug Info Approved Essential hypertension ICD11: BA00 [1]
Tinidazole
Drug Info Approved Protozoan infection ICD11: 1F5Z [1]
Trandolapril
Drug Info Approved Essential hypertension ICD11: BA00 [1]
Olmesartan medoxomil
Drug Info Approved Essential hypertension ICD11: BA00 [1]
Telmisartan
Drug Info Approved Essential hypertension ICD11: BA00 [1]
Cetirizine
Drug Info Approved Allergy ICD11: 4A80 [1]
Diflorasone diacetate
Drug Info Approved Rosacea ICD11: ED90 [1]
      Drugs in Phase 4 Clinical Trial Click to Show/Hide the Full List of Drugs:          6 Drugs
Famprofazone
Drug Info Phase 4 Anaesthesia ICD11: 8E22 [1]
Artemisinin
Drug Info Phase 4 Malaria ICD11: 1F40 [1]
Phenazopyridine
Drug Info Phase 4 Infectious cystitis ICD11: GC00 [1]
Racecadotril
Drug Info Phase 4 Irritable bowel syndrome ICD11: DD91 [1]
Bisacodyl
Drug Info Phase 4 Irritable bowel syndrome ICD11: DD91 [1]
Ergonovine maleate
Drug Info Phase 4 Abnormal vaginal bleeding ICD11: GA2Y [1]
      Drugs in Phase 2 Clinical Trial Click to Show/Hide the Full List of Drugs:          2 Drugs
Roxatidine
Drug Info Phase 2 Gastro-oesophageal reflux disease ICD11: DA22 [1]
TU-199
Drug Info Phase 2 Gastro-oesophageal reflux disease ICD11: DA22 [1]
      Drugs in Phase 1 Clinical Trial Click to Show/Hide the Full List of Drugs:          1 Drugs
BRN-0498823
Drug Info Phase 1 Essential hypertension ICD11: BA00 [1]
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          2 Drugs
ML-236B
Drug Info Preclinical Hypertriglyceridaemia ICD11: 5C80 [1]
Diacetamate
Drug Info Investigative Discovery agent ICD: N.A. [1]
References
1 Mapping human microbiome drug metabolism by gut bacteria and their genes. Nature. 2019 Jun;570(7762):462-467.

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