Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DME1843)
DME Name Beta-glucosidase (bglA), Enhydrobacter aerosaccus
Synonyms Periplasmic beta-glucosidase; Glucan endo-1 3-beta-D-glucosidase; Beta-D-glucosidase; SAMN02745126_03145
Gene Name bglA
UniProt ID
A0A1T4QCU7_9PROT
EC Number    EC: 3.2.1.21     (Click to Show/Hide the Complete EC Tree)
Hydrolases
Glycosylase
O/S-glycosyl compound glycosidase
EC: 3.2.1.21
Lineage    Species: Enhydrobacter aerosaccus     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Alphaproteobacteria
Order: Rhodospirillales
Family: Enhydrobacter
Genus: Enhydrobacter
Species: Enhydrobacter aerosaccus
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Tissue Distribution Primarily distributed in human gut.
Sequence
MPARLSRRDLAGAAVLTAALGATIAATEADAAPKSQSGFPDGFLWGTATAAYQVEGAVHE
DGRGPSIWDTFSHLPGKIRDGSTGDVSVDHYHRYKEDVALMKALGATSYRFSIAWPRVFP
DGTGTPNPKGLDFYDRLVDELLKAGIKPFATLYHWDLPQALQDRGGWQSRDTAQAFGAYA
GYVANKLGDRVENFFTLNEMLTFVEHGHAAGVFAPGLTLPPQGVNQVRHHAVLAHGLGVQ
AMRASARRPIRIGPAENITIGIPAVETPENIRAAEIATREFNAPYLTVMLEGRYTDAYLA
ATGADAPKFTAEDLKIIASPVDFVGLNVYTPSFFVVATDAAPHYRALPLPSSYPHMASPW
LTIGPEALYWAPRHAATLWNAKEIYITENGTSSADQLAEDGQIYDTDRIMYLRNYLTQLQ
RATAEGVPVRGYFLWSLLDNFEWADGYATRFGLVHVDYTTQKRTPKLSAAFYREVIARNA
VA
Function This enzyme has wide specificity for beta-D-glucosides such as beta-D-galactosides, alpha-L-arabinosides, beta-D-xylosides, beta-D-fucosides.
Full List of Drug(s) Metabolized by This DME
      Preclinical/investigative Agents Click to Show/Hide the Full List of Drugs:          1 Drugs
Ginsenoside Rb1
 Drug Info Investigative Obesity ICD11: 5B81 [1]
References
1 Genus Enhydrobacter Staley et al. 1987 should be recognized as a member of the family Rhodospirillaceae within the class Alphaproteobacteria. Microbiol Immunol. 2012 Jan;56(1):21-6.

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