General Information of DME (ID: DMEN310)
DME Name	12alpha-hydroxysteroid dehydrogenase (12-HSDH), .
Gene Name	12-HSDH
Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME

Full List of Drug(s) Metabolized by This DME
Preclinical/investigative Agents			Click to Show/Hide the Full List of Drugs:          1 Drugs
Oxolithocholic acid	Drug Info	Investigative	Discovery agent	ICD: N.A.	[1]

Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF MR006021 7,12-dioxo-LCA 7-oxo-DCA Unclear - Unclear Oxolithocholic acid [1] MR006022 Oxolithocholic acid CA Unclear - Unclear Oxolithocholic acid [1]

References
1	Metabolism of oxo-bile acids and characterization of recombinant 12alpha-hydroxysteroid dehydrogenases from bile acid 7alpha-dehydroxylating human gut bacteria. Appl Environ Microbiol. 2018 May 1;84(10). pii: e00235-18.

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