| General Information of DME (ID: DMEN311) |
| DME Name |
3-hydroxysteriod dehydrogenase (3HSD), Homo sapiens
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| Gene Name |
3HSD
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| Lineage |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Full List of Drug(s) Metabolized by This DME |
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Drugs in Phase 4 Clinical Trial
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Click to Show/Hide the Full List of Drugs: 1 Drugs
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Tibolone |
Drug Info
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Phase 4 |
Depression
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ICD11: 6A71
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[1], [2], [3] |
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Drugs in Phase 2 Clinical Trial
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Click to Show/Hide the Full List of Drugs: 1 Drugs
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TOK-001 |
Drug Info
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Phase 2 |
Prostate cancer
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ICD11: 2C82
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[4] |
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| Full List of Metabolic Reactions (MR) Catalyzed by This DME |
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| References |
| 1 |
Sulfation of tibolone and tibolone metabolites by expressed human cytosolic sulfotransferases. J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):383-91.
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| 2 |
Sulfation of tibolone metabolites by human postmenopausal liver and small intestinal sulfotransferases (SULTs). Steroids. 2006 May;71(5):343-51.
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| 3 |
Antioxidant effect of the active metabolites of tibolone
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| 4 |
Steroidogenic Metabolism of Galeterone Reveals a Diversity of Biochemical Activities
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