Details of Drug-Metabolizing Enzyme (DME)

General Information of DME (ID: DMEN365)
DME Name aldehyde dehydrogenase (ALDH), Homo sapiens
Gene Name ALDH
Lineage    Species: Homo sapiens     (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR007450 Acetaldehyde Acetic acid Oxidation - Oxidationn Ethanol [1]
MR007451 Acetaldehyde Acetate Unclear - Unclear Ethanol [1]
MR007450 Acetaldehyde Acetic acid Unclear - Unclear Ethanol [1]
MR007451 Acetaldehyde Acetate Unclear - Unclear Ethanol [1]
MR007530 LF-08-0299 M3 LF-08-0299 M7 Unclear - Unclear LF-08-0299 [2]
MR007655 Putrescine -aminobutyric acid Unclear - Unclear Putrescine [3]
⏷ Show the Full List of 6 MR(s)
References
1 Ethanol Metabolism in the Liver, the Induction of Oxidant Stress, and the Antioxidant Defense System
2 Metabolism of tresperimus by rat aorta semicarbazide-sensitive amine oxidase (SSAO). Fundam Clin Pharmacol. 2002 Dec;16(6):461-70.
3 Human aldehyde dehydrogenase: metabolism of putrescine and histamine

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