General Information of DME (ID: DMEN765)
DME Name UDP-glucuronosyltransferase 1-2 (UGT1A2), .
Gene Name UGT1A2
      Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
Full List of Drug(s) Metabolized by This DME
      Drugs Approved by FDA Click to Show/Hide the Full List of Drugs:          1 Drugs
Hesperidin
Drug Info Approved Vascular purpura ICD11: 3B60 [1]
      Discontinued/withdrawn Drugs Click to Show/Hide the Full List of Drugs:          1 Drugs
R-ketoprofen
Drug Info Discontinued in Phase 2 Discovery agent ICD: N.A. [2]
Full List of Metabolic Reactions (MR) Catalyzed by This DME
MR ID Reactant Product MR Type Source Drug REF
MR013739 R-ketoprofen R-ketoprofen metabolite M1 Conjugation - Glucuronidation R-ketoprofen [2], [3]
References
1 U. S. FDA Label -Hesperidin
2 High-performance liquid chromatographic enantioselective assay for the measurement of ketoprofen glucuronidation by liver microsomes
3 Ketoprofen in horses: Metabolism, pharmacokinetics, and effects on inflammatory biomarkers

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