Details of Drug-Metabolizing Enzyme (DME)
Full List of Drug(s) Metabolized by This DME | |||||
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Preclinical/investigative Agents | Click to Show/Hide the Full List of Drugs: 1 Drugs | ||||
D-glucose |
Drug Info | Investigative | Discovery agent | ICD: N.A. | [1] |
Experimental Enzyme Kinetic Data of Drugs | Click to Show/Hide the Full List of Drugs: 1 Drugs | ||||
D-glucose |
Drug Info | Investigative | Discovery agent | Km = 0.27 microM | [1] |
Tissue/Disease-Specific Protein Abundances of This DME | |||||
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Tissue-specific Protein Abundances in Healthy Individuals | Click to Show/Hide | ||||
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ICD Disease Classification 01 | Infectious/parasitic disease | Click to Show/Hide | |||
ICD-11: 1C1H | Necrotising ulcerative gingivitis | Click to Show/Hide | |||
The Studied Tissue | Gingival tissue | ||||
The Specified Disease | Bacterial infection of gingival [ICD-11:1C1H] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.50E-13; Fold-change: 4.30E-01; Z-score: 1.68E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 1E30 | Influenza | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Influenza [ICD-11:1E30] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.37E-02; Fold-change: -2.54E-01; Z-score: -1.14E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 1E51 | Chronic viral hepatitis | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Chronic hepatitis C [ICD-11:1E51.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.61E-01; Fold-change: -1.12E-02; Z-score: -1.06E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 1G41 | Sepsis with septic shock | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Sepsis with septic shock [ICD-11:1G41] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.68E-01; Fold-change: 2.43E-02; Z-score: 6.31E-02 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: CA40 | Respiratory syncytial virus infection | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Pediatric respiratory syncytial virus infection [ICD-11:CA40.11] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.69E-01; Fold-change: 6.60E-02; Z-score: 3.59E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: CA42 | Rhinovirus infection | Click to Show/Hide | |||
The Studied Tissue | Nasal epithelium tissue | ||||
The Specified Disease | Rhinovirus infection [ICD-11:CA42.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.88E-02; Fold-change: 1.69E-02; Z-score: 1.45E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: KA60 | Neonatal sepsis | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Neonatal sepsis [ICD-11:KA60] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.42E-10; Fold-change: 2.75E-01; Z-score: 7.25E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD Disease Classification 02 | Neoplasm | Click to Show/Hide | |||
ICD-11: 2A00 | Brain cancer | Click to Show/Hide | |||
The Studied Tissue | Nervous tissue | ||||
The Specified Disease | Glioblastopma [ICD-11:2A00.00] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.91E-46; Fold-change: 2.60E-01; Z-score: 7.92E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
The Studied Tissue | Brain stem tissue | ||||
The Specified Disease | Glioma [ICD-11:2A00.0Y-2A00.0Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 8.84E-01; Fold-change: -1.04E-01; Z-score: -2.14E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | White matter tissue | ||||
The Specified Disease | Glioma [ICD-11:2A00.0Y-2A00.0Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.71E-02; Fold-change: 7.26E-01; Z-score: 8.85E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
The Studied Tissue | Brain stem tissue | ||||
The Specified Disease | Neuroectodermal tumour [ICD-11:2A00.11] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.09E-01; Fold-change: 1.85E-01; Z-score: 7.24E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 2A20 | Myeloproliferative neoplasm | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Myelofibrosis [ICD-11:2A20.2] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.51E-08; Fold-change: -4.61E-01; Z-score: -3.37E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Polycythemia vera [ICD-11:2A20.4] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.96E-22; Fold-change: -3.76E-01; Z-score: -2.39E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 2A36 | Myelodysplastic syndrome | Click to Show/Hide | |||
The Studied Tissue | Bone marrow | ||||
The Specified Disease | Myelodysplastic syndrome [ICD-11:2A36-2A3Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.00E-03; Fold-change: -9.02E-02; Z-score: -2.78E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 5.24E-01; Fold-change: 4.33E-02; Z-score: 8.16E-02 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2A81 | Diffuse large B-cell lymphoma | Click to Show/Hide | |||
The Studied Tissue | Tonsil tissue | ||||
The Specified Disease | Diffuse large B-cell lymphoma [ICD-11:2A81] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.28E-01; Fold-change: 2.34E-01; Z-score: 7.54E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2A83 | Plasma cell neoplasm | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Multiple myeloma [ICD-11:2A83.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.92E-02; Fold-change: 7.78E-02; Z-score: 4.45E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
The Studied Tissue | Bone marrow | ||||
The Specified Disease | Multiple myeloma [ICD-11:2A83.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.28E-02; Fold-change: 1.57E-01; Z-score: 7.25E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2B33 | Leukaemia | Click to Show/Hide | |||
The Studied Tissue | Bone marrow | ||||
The Specified Disease | Acute myelocytic leukaemia [ICD-11:2B33.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.49E-07; Fold-change: 1.86E-01; Z-score: 5.42E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2B6E | Oral cancer | Click to Show/Hide | |||
The Studied Tissue | Oral tissue | ||||
The Specified Disease | Oral cancer [ICD-11:2B6E] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.02E-07; Fold-change: 4.58E-01; Z-score: 1.39E+00 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 6.88E-04; Fold-change: 1.66E-01; Z-score: 4.64E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2B70 | Esophageal cancer | Click to Show/Hide | |||
The Studied Tissue | Esophagus | ||||
The Specified Disease | Esophagal cancer [ICD-11:2B70] | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 2.65E-01; Fold-change: -2.59E-01; Z-score: -6.47E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2B72 | Stomach cancer | Click to Show/Hide | |||
The Studied Tissue | Gastric tissue | ||||
The Specified Disease | Gastric cancer [ICD-11:2B72] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.57E-01; Fold-change: 2.15E-01; Z-score: 5.25E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 1.10E-04; Fold-change: 3.25E-01; Z-score: 1.35E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2B90 | Colon cancer | Click to Show/Hide | |||
The Studied Tissue | Colon tissue | ||||
The Specified Disease | Colon cancer [ICD-11:2B90] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.04E-07; Fold-change: 1.28E-01; Z-score: 4.87E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.88E-20; Fold-change: 5.25E-01; Z-score: 1.20E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2B92 | Rectal cancer | Click to Show/Hide | |||
The Studied Tissue | Rectal colon tissue | ||||
The Specified Disease | Rectal cancer [ICD-11:2B92] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.11E-02; Fold-change: 3.07E-01; Z-score: 1.10E+00 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.52E-02; Fold-change: 2.30E-01; Z-score: 1.49E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C10 | Pancreatic cancer | Click to Show/Hide | |||
The Studied Tissue | Pancreas | ||||
The Specified Disease | Pancreatic cancer [ICD-11:2C10] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.03E-02; Fold-change: 5.66E-01; Z-score: 9.02E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 2.98E-01; Fold-change: 1.98E-01; Z-score: 4.27E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C12 | Liver cancer | Click to Show/Hide | |||
The Studied Tissue | Liver tissue | ||||
The Specified Disease | Liver cancer [ICD-11:2C12.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.61E-04; Fold-change: 3.38E-01; Z-score: 8.64E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 1.35E-16; Fold-change: 3.24E-01; Z-score: 1.07E+00 | ||||
The Expression Level of Disease Section Compare with the Other Disease Section | p-value: 3.99E-01; Fold-change: 1.45E-01; Z-score: 4.84E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
DME expression in tissue other than the diseased tissue of patients
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C25 | Lung cancer | Click to Show/Hide | |||
The Studied Tissue | Lung tissue | ||||
The Specified Disease | Lung cancer [ICD-11:2C25] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.08E-03; Fold-change: -9.04E-02; Z-score: -2.45E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 4.42E-03; Fold-change: -1.90E-01; Z-score: -4.58E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C30 | Skin cancer | Click to Show/Hide | |||
The Studied Tissue | Skin | ||||
The Specified Disease | Melanoma [ICD-11:2C30] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.07E-04; Fold-change: 5.84E-01; Z-score: 1.20E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
The Studied Tissue | Skin | ||||
The Specified Disease | Skin cancer [ICD-11:2C30-2C3Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.22E-37; Fold-change: 5.41E-01; Z-score: 1.79E+00 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 1.67E-12; Fold-change: 2.76E-01; Z-score: 7.55E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C6Z | Breast cancer | Click to Show/Hide | |||
The Studied Tissue | Breast tissue | ||||
The Specified Disease | Breast cancer [ICD-11:2C60-2C6Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.93E-70; Fold-change: 6.21E-01; Z-score: 1.68E+00 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 2.55E-03; Fold-change: 1.78E-01; Z-score: 4.02E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C73 | Ovarian cancer | Click to Show/Hide | |||
The Studied Tissue | Ovarian tissue | ||||
The Specified Disease | Ovarian cancer [ICD-11:2C73] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.94E-04; Fold-change: 6.92E-01; Z-score: 1.95E+00 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.71E-01; Fold-change: 7.04E-01; Z-score: 8.34E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C77 | Cervical cancer | Click to Show/Hide | |||
The Studied Tissue | Cervical tissue | ||||
The Specified Disease | Cervical cancer [ICD-11:2C77] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.56E-06; Fold-change: 1.27E-01; Z-score: 8.39E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C78 | Uterine cancer | Click to Show/Hide | |||
The Studied Tissue | Endometrium tissue | ||||
The Specified Disease | Uterine cancer [ICD-11:2C78] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.86E-02; Fold-change: -2.08E-01; Z-score: -5.01E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 2.72E-08; Fold-change: -1.49E+00; Z-score: -1.35E+01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 2C82 | Prostate cancer | Click to Show/Hide | |||
The Studied Tissue | Prostate | ||||
The Specified Disease | Prostate cancer [ICD-11:2C82] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.22E-01; Fold-change: 2.13E-01; Z-score: 3.91E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C90 | Renal cancer | Click to Show/Hide | |||
The Studied Tissue | Kidney | ||||
The Specified Disease | Renal cancer [ICD-11:2C90-2C91] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.88E-05; Fold-change: 6.70E-01; Z-score: 2.07E+00 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 9.09E-13; Fold-change: 2.95E-01; Z-score: 1.21E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 2C92 | Ureter cancer | Click to Show/Hide | |||
The Studied Tissue | Urothelium | ||||
The Specified Disease | Ureter cancer [ICD-11:2C92] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.86E-01; Fold-change: -1.53E-01; Z-score: -7.03E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2C94 | Bladder cancer | Click to Show/Hide | |||
The Studied Tissue | Bladder tissue | ||||
The Specified Disease | Bladder cancer [ICD-11:2C94] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 8.42E-02; Fold-change: 1.23E-01; Z-score: 1.03E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2D02 | Retinal cancer | Click to Show/Hide | |||
The Studied Tissue | Uvea | ||||
The Specified Disease | Retinoblastoma [ICD-11:2D02.2] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 8.75E-11; Fold-change: 1.51E+00; Z-score: 8.12E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2D10 | Thyroid cancer | Click to Show/Hide | |||
The Studied Tissue | Thyroid | ||||
The Specified Disease | Thyroid cancer [ICD-11:2D10] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.35E-06; Fold-change: 2.40E-01; Z-score: 8.27E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 1.21E-02; Fold-change: 1.76E-01; Z-score: 5.46E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2D11 | Adrenal cancer | Click to Show/Hide | |||
The Studied Tissue | Adrenal cortex | ||||
The Specified Disease | Adrenocortical carcinoma [ICD-11:2D11.Z] | ||||
The Expression Level of Disease Section Compare with the Other Disease Section | p-value: 3.94E-06; Fold-change: 3.41E-01; Z-score: 1.51E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in tissue other than the diseased tissue of patients
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Violin Diagram of DME Disease-specific Protein Abundances |
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Click to View the Clearer Original Diagram | |||
ICD-11: 2D12 | Endocrine gland neoplasm | Click to Show/Hide | |||
The Studied Tissue | Pituitary tissue | ||||
The Specified Disease | Pituitary cancer [ICD-11:2D12] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.63E-01; Fold-change: -1.30E-01; Z-score: -5.01E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Pituitary tissue | ||||
The Specified Disease | Pituitary gonadotrope tumour [ICD-11:2D12] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.13E-02; Fold-change: -2.63E-01; Z-score: -9.23E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 2D42 | Head and neck cancer | Click to Show/Hide | |||
The Studied Tissue | Head and neck tissue | ||||
The Specified Disease | Head and neck cancer [ICD-11:2D42] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.68E-04; Fold-change: 5.37E-02; Z-score: 1.07E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 03 | Blood/blood-forming organ disease | Click to Show/Hide | |||
ICD-11: 3A51 | Sickle cell disorder | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Sickle cell disease [ICD-11:3A51.0-3A51.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.13E-03; Fold-change: -4.41E-01; Z-score: -1.62E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 3A70 | Aplastic anaemia | Click to Show/Hide | |||
The Studied Tissue | Bone marrow | ||||
The Specified Disease | Shwachman-Diamond syndrome [ICD-11:3A70.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.07E-02; Fold-change: -3.56E-01; Z-score: -1.50E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 3B63 | Thrombocytosis | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Thrombocythemia [ICD-11:3B63] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.36E-15; Fold-change: -2.94E-01; Z-score: -2.16E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 3B64 | Thrombocytopenia | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Thrombocytopenia [ICD-11:3B64] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 8.64E-01; Fold-change: 1.87E-02; Z-score: 5.02E-02 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 04 | Immune system disease | Click to Show/Hide | |||
ICD-11: 4A00 | Immunodeficiency | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Immunodeficiency [ICD-11:4A00-4A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.70E-03; Fold-change: -2.91E-01; Z-score: -1.37E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 4A40 | Lupus erythematosus | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Lupus erythematosus [ICD-11:4A40] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.19E-05; Fold-change: 4.03E-01; Z-score: 6.89E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 4A42 | Systemic sclerosis | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Scleroderma [ICD-11:4A42.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.06E-06; Fold-change: 2.05E-01; Z-score: 2.75E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 4A43 | Systemic autoimmune disease | Click to Show/Hide | |||
The Studied Tissue | Salivary gland tissue | ||||
The Specified Disease | Sjogren's syndrome [ICD-11:4A43.2] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.60E-02; Fold-change: -1.43E-01; Z-score: -1.02E+00 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 9.08E-02; Fold-change: 3.82E-01; Z-score: 1.48E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 4A62 | Behcet disease | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Behcet's disease [ICD-11:4A62] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.32E-01; Fold-change: -9.02E-02; Z-score: -5.12E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 4B04 | Monocyte count disorder | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Autosomal dominant monocytopenia [ICD-11:4B04] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.27E-01; Fold-change: -1.39E-02; Z-score: -5.02E-02 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 05 | Endocrine/nutritional/metabolic disease | Click to Show/Hide | |||
ICD-11: 5A11 | Type 2 diabetes mellitus | Click to Show/Hide | |||
The Studied Tissue | Omental adipose tissue | ||||
The Specified Disease | Obesity related type 2 diabetes [ICD-11:5A11] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.96E-01; Fold-change: -1.99E-01; Z-score: -8.02E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Liver tissue | ||||
The Specified Disease | Type 2 diabetes [ICD-11:5A11] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.27E-01; Fold-change: -1.50E-01; Z-score: -5.52E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 5A80 | Ovarian dysfunction | Click to Show/Hide | |||
The Studied Tissue | Vastus lateralis muscle | ||||
The Specified Disease | Polycystic ovary syndrome [ICD-11:5A80.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.88E-01; Fold-change: 1.21E-03; Z-score: 1.07E-02 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 5C51 | Inborn carbohydrate metabolism disorder | Click to Show/Hide | |||
The Studied Tissue | Biceps muscle | ||||
The Specified Disease | Pompe disease [ICD-11:5C51.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.85E-01; Fold-change: -4.28E-02; Z-score: -2.11E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 5C56 | Lysosomal disease | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Batten disease [ICD-11:5C56.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.45E-01; Fold-change: 1.06E-01; Z-score: 5.84E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 5C80 | Hyperlipoproteinaemia | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Familial hypercholesterolemia [ICD-11:5C80.00] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.81E-02; Fold-change: -1.68E-01; Z-score: -1.54E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Whole blood | ||||
The Specified Disease | Familial hypercholesterolemia [ICD-11:5C80.00] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.41E-03; Fold-change: 3.88E-01; Z-score: 1.00E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 06 | Mental/behavioural/neurodevelopmental disorder | Click to Show/Hide | |||
ICD-11: 6A02 | Autism spectrum disorder | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Autism [ICD-11:6A02] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.29E-01; Fold-change: 4.64E-02; Z-score: 1.01E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 6A20 | Schizophrenia | Click to Show/Hide | |||
The Studied Tissue | Prefrontal cortex | ||||
The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.62E-01; Fold-change: -2.36E-02; Z-score: -2.76E-02 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Superior temporal cortex | ||||
The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.16E-01; Fold-change: 2.06E-02; Z-score: 2.60E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 6A60 | Bipolar disorder | Click to Show/Hide | |||
The Studied Tissue | Prefrontal cortex | ||||
The Specified Disease | Bipolar disorder [ICD-11:6A60-6A6Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.96E-02; Fold-change: -1.24E-01; Z-score: -1.26E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 6A70 | Depressive disorder | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Major depressive disorder [ICD-11:6A70-6A7Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.36E-01; Fold-change: 8.06E-02; Z-score: 3.17E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Hippocampus | ||||
The Specified Disease | Major depressive disorder [ICD-11:6A70-6A7Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 8.55E-01; Fold-change: -2.15E-02; Z-score: -2.15E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 08 | Nervous system disease | Click to Show/Hide | |||
ICD-11: 8A00 | Parkinsonism | Click to Show/Hide | |||
The Studied Tissue | Substantia nigra tissue | ||||
The Specified Disease | Parkinson's disease [ICD-11:8A00.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.53E-01; Fold-change: -2.07E-01; Z-score: -6.28E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8A01 | Choreiform disorder | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Huntington's disease [ICD-11:8A01.10] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.90E-01; Fold-change: 2.42E-01; Z-score: 6.44E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8A20 | Alzheimer disease | Click to Show/Hide | |||
The Studied Tissue | Entorhinal cortex | ||||
The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.34E-01; Fold-change: -5.24E-02; Z-score: -2.91E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8A2Y | Neurocognitive impairment | Click to Show/Hide | |||
The Studied Tissue | White matter tissue | ||||
The Specified Disease | HIV-associated neurocognitive impairment [ICD-11:8A2Y-8A2Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.04E-01; Fold-change: -6.76E-02; Z-score: -4.29E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8A40 | Multiple sclerosis | Click to Show/Hide | |||
The Studied Tissue | Plasmacytoid dendritic cells | ||||
The Specified Disease | Multiple sclerosis [ICD-11:8A40] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.03E-01; Fold-change: -1.36E-01; Z-score: -7.07E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Spinal cord | ||||
The Specified Disease | Multiple sclerosis [ICD-11:8A40] | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 9.62E-01; Fold-change: 8.04E-02; Z-score: 1.86E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8A60 | Epilepsy | Click to Show/Hide | |||
The Studied Tissue | Peritumoral cortex tissue | ||||
The Specified Disease | Epilepsy [ICD-11:8A60-8A6Z] | ||||
The Expression Level of Disease Section Compare with the Other Disease Section | p-value: 4.79E-01; Fold-change: 2.06E-03; Z-score: 5.75E-03 | ||||
DME expression in the diseased tissue of patients
DME expression in tissue other than the diseased tissue of patients
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Whole blood | ||||
The Specified Disease | Seizure [ICD-11:8A60-8A6Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.23E-01; Fold-change: -1.03E-01; Z-score: -3.25E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8B01 | Subarachnoid haemorrhage | Click to Show/Hide | |||
The Studied Tissue | Intracranial artery | ||||
The Specified Disease | Intracranial aneurysm [ICD-11:8B01.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.67E-04; Fold-change: 6.70E-01; Z-score: 3.10E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8B11 | Cerebral ischaemic stroke | Click to Show/Hide | |||
The Studied Tissue | Whole blood | ||||
The Specified Disease | Cardioembolic stroke [ICD-11:8B11.20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.06E-05; Fold-change: -1.58E-01; Z-score: -1.32E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Ischemic stroke [ICD-11:8B11] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.33E-01; Fold-change: -1.40E-01; Z-score: -6.18E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8B60 | Motor neuron disease | Click to Show/Hide | |||
The Studied Tissue | Skin | ||||
The Specified Disease | Lateral sclerosis [ICD-11:8B60.4] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.04E-01; Fold-change: 9.00E-02; Z-score: 8.47E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Cervical spinal cord | ||||
The Specified Disease | Lateral sclerosis [ICD-11:8B60.4] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.71E-01; Fold-change: -1.28E-01; Z-score: -4.49E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8C70 | Muscular dystrophy | Click to Show/Hide | |||
The Studied Tissue | Muscle tissue | ||||
The Specified Disease | Myopathy [ICD-11:8C70.6] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 8.62E-03; Fold-change: 4.06E-01; Z-score: 1.56E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: 8C75 | Distal myopathy | Click to Show/Hide | |||
The Studied Tissue | Muscle tissue | ||||
The Specified Disease | Tibial muscular dystrophy [ICD-11:8C75] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.29E-11; Fold-change: 8.31E-01; Z-score: 4.26E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 09 | Visual system disease | Click to Show/Hide | |||
ICD-11: 9A96 | Anterior uveitis | Click to Show/Hide | |||
The Studied Tissue | Peripheral monocyte | ||||
The Specified Disease | Autoimmune uveitis [ICD-11:9A96] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.58E-01; Fold-change: -2.46E-01; Z-score: -4.65E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 11 | Circulatory system disease | Click to Show/Hide | |||
ICD-11: BA41 | Myocardial infarction | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Myocardial infarction [ICD-11:BA41-BA50] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.99E-01; Fold-change: 3.57E-04; Z-score: 6.90E-04 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: BA80 | Coronary artery disease | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Coronary artery disease [ICD-11:BA80-BA8Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.93E-01; Fold-change: -1.56E-01; Z-score: -5.25E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: BB70 | Aortic valve stenosis | Click to Show/Hide | |||
The Studied Tissue | Calcified aortic valve | ||||
The Specified Disease | Aortic stenosis [ICD-11:BB70] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.71E-01; Fold-change: 3.84E-02; Z-score: 1.07E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 12 | Respiratory system disease | Click to Show/Hide | |||
ICD-11: 7A40 | Central sleep apnoea | Click to Show/Hide | |||
The Studied Tissue | Hyperplastic tonsil | ||||
The Specified Disease | Apnea [ICD-11:7A40] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.31E-01; Fold-change: 1.84E-01; Z-score: 8.28E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: CA08 | Vasomotor or allergic rhinitis | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Olive pollen allergy [ICD-11:CA08.00] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.40E-01; Fold-change: 1.93E-02; Z-score: 7.54E-02 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: CA0A | Chronic rhinosinusitis | Click to Show/Hide | |||
The Studied Tissue | Sinus mucosa tissue | ||||
The Specified Disease | Chronic rhinosinusitis [ICD-11:CA0A] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.58E-02; Fold-change: 1.25E-01; Z-score: 1.27E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: CA22 | Chronic obstructive pulmonary disease | Click to Show/Hide | |||
The Studied Tissue | Lung tissue | ||||
The Specified Disease | Chronic obstructive pulmonary disease [ICD-11:CA22] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.69E-01; Fold-change: 2.46E-02; Z-score: 9.08E-02 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Small airway epithelium | ||||
The Specified Disease | Chronic obstructive pulmonary disease [ICD-11:CA22] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.78E-03; Fold-change: -1.73E-01; Z-score: -6.57E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: CA23 | Asthma | Click to Show/Hide | |||
The Studied Tissue | Nasal and bronchial airway | ||||
The Specified Disease | Asthma [ICD-11:CA23] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.88E-03; Fold-change: 8.65E-02; Z-score: 1.59E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: CB03 | Idiopathic interstitial pneumonitis | Click to Show/Hide | |||
The Studied Tissue | Lung tissue | ||||
The Specified Disease | Idiopathic pulmonary fibrosis [ICD-11:CB03.4] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.65E-01; Fold-change: -1.09E-01; Z-score: -7.38E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 13 | Digestive system disease | Click to Show/Hide | |||
ICD-11: DA0C | Periodontal disease | Click to Show/Hide | |||
The Studied Tissue | Gingival tissue | ||||
The Specified Disease | Periodontal disease [ICD-11:DA0C] | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.32E-09; Fold-change: 3.62E-01; Z-score: 1.39E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: DA42 | Gastritis | Click to Show/Hide | |||
The Studied Tissue | Gastric antrum tissue | ||||
The Specified Disease | Eosinophilic gastritis [ICD-11:DA42.2] | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.14E-02; Fold-change: -2.06E-01; Z-score: -2.81E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: DB92 | Non-alcoholic fatty liver disease | Click to Show/Hide | |||
The Studied Tissue | Liver tissue | ||||
The Specified Disease | Non-alcoholic fatty liver disease [ICD-11:DB92] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 5.56E-02; Fold-change: 1.62E-01; Z-score: 2.50E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: DB99 | Hepatic failure | Click to Show/Hide | |||
The Studied Tissue | Liver tissue | ||||
The Specified Disease | Liver failure [ICD-11:DB99.7-DB99.8] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.21E-04; Fold-change: 3.46E-01; Z-score: 2.07E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: DD71 | Ulcerative colitis | Click to Show/Hide | |||
The Studied Tissue | Colon mucosal tissue | ||||
The Specified Disease | Ulcerative colitis [ICD-11:DD71] | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 8.61E-02; Fold-change: 5.20E-02; Z-score: 1.92E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in tissue other than the diseased tissue of patients
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: DD91 | Irritable bowel syndrome | Click to Show/Hide | |||
The Studied Tissue | Rectal colon tissue | ||||
The Specified Disease | Irritable bowel syndrome [ICD-11:DD91.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.34E-01; Fold-change: 3.94E-02; Z-score: 1.79E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 14 | Skin disease | Click to Show/Hide | |||
ICD-11: EA80 | Atopic eczema | Click to Show/Hide | |||
The Studied Tissue | Skin | ||||
The Specified Disease | Atopic dermatitis [ICD-11:EA80] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.40E-04; Fold-change: 1.66E-01; Z-score: 7.46E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: EA90 | Psoriasis | Click to Show/Hide | |||
The Studied Tissue | Skin | ||||
The Specified Disease | Psoriasis [ICD-11:EA90] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.32E-10; Fold-change: 2.43E-01; Z-score: 8.61E-01 | ||||
The Expression Level of Disease Section Compare with the Adjacent Tissue | p-value: 3.91E-01; Fold-change: -1.41E-01; Z-score: -4.43E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue adjacent to the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: ED63 | Acquired hypomelanotic disorder | Click to Show/Hide | |||
The Studied Tissue | Skin | ||||
The Specified Disease | Vitiligo [ICD-11:ED63.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.71E-01; Fold-change: 8.37E-02; Z-score: 8.24E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: ED70 | Alopecia or hair loss | Click to Show/Hide | |||
The Studied Tissue | Skin from scalp | ||||
The Specified Disease | Alopecia [ICD-11:ED70] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.65E-01; Fold-change: -4.62E-02; Z-score: -1.44E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: EK0Z | Contact dermatitis | Click to Show/Hide | |||
The Studied Tissue | Skin | ||||
The Specified Disease | Sensitive skin [ICD-11:EK0Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 2.71E-01; Fold-change: 2.34E-01; Z-score: 1.77E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 15 | Musculoskeletal system/connective tissue disease | Click to Show/Hide | |||
ICD-11: FA00 | Osteoarthritis | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Arthropathy [ICD-11:FA00-FA5Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 6.07E-01; Fold-change: 6.53E-02; Z-score: 3.94E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Synovial tissue | ||||
The Specified Disease | Osteoarthritis [ICD-11:FA00-FA0Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.48E-01; Fold-change: 4.40E-01; Z-score: 4.56E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: FA20 | Rheumatoid arthritis | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Childhood onset rheumatic disease [ICD-11:FA20.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 3.46E-01; Fold-change: -3.20E-02; Z-score: -1.82E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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The Studied Tissue | Synovial tissue | ||||
The Specified Disease | Rheumatoid arthritis [ICD-11:FA20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.00E-05; Fold-change: 1.66E+00; Z-score: 4.66E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: FA24 | Juvenile idiopathic arthritis | Click to Show/Hide | |||
The Studied Tissue | Peripheral blood | ||||
The Specified Disease | Juvenile idiopathic arthritis [ICD-11:FA24] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.25E-01; Fold-change: -4.82E-02; Z-score: -1.79E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: FA92 | Inflammatory spondyloarthritis | Click to Show/Hide | |||
The Studied Tissue | Pheripheral blood | ||||
The Specified Disease | Ankylosing spondylitis [ICD-11:FA92.0Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.34E-01; Fold-change: 7.18E-02; Z-score: 1.94E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: FB83 | Low bone mass disorder | Click to Show/Hide | |||
The Studied Tissue | Bone marrow | ||||
The Specified Disease | Osteoporosis [ICD-11:FB83.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.60E-01; Fold-change: -1.28E-01; Z-score: -4.46E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 16 | Genitourinary system disease | Click to Show/Hide | |||
ICD-11: GA10 | Endometriosis | Click to Show/Hide | |||
The Studied Tissue | Endometrium tissue | ||||
The Specified Disease | Endometriosis [ICD-11:GA10] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.05E-01; Fold-change: -7.32E-02; Z-score: -1.61E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: GC00 | Cystitis | Click to Show/Hide | |||
The Studied Tissue | Bladder tissue | ||||
The Specified Disease | Interstitial cystitis [ICD-11:GC00.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 1.51E-04; Fold-change: 5.61E-01; Z-score: 5.55E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 19 | Condition originating in perinatal period | Click to Show/Hide | |||
ICD-11: KA21 | Short gestation disorder | Click to Show/Hide | |||
The Studied Tissue | Myometrium | ||||
The Specified Disease | Preterm birth [ICD-11:KA21.4Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 4.99E-01; Fold-change: -4.78E-01; Z-score: -8.43E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD Disease Classification 20 | Developmental anomaly | Click to Show/Hide | |||
ICD-11: LD2C | Overgrowth syndrome | Click to Show/Hide | |||
The Studied Tissue | Adipose tissue | ||||
The Specified Disease | Simpson golabi behmel syndrome [ICD-11:LD2C] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 9.47E-01; Fold-change: -8.47E-02; Z-score: -3.91E-01 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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ICD-11: LD2D | Phakomatoses/hamartoneoplastic syndrome | Click to Show/Hide | |||
The Studied Tissue | Perituberal tissue | ||||
The Specified Disease | Tuberous sclerosis complex [ICD-11:LD2D.2] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value: 7.01E-02; Fold-change: -3.61E-01; Z-score: -1.68E+00 | ||||
DME expression in the diseased tissue of patients
DME expression in the normal tissue of healthy individuals
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Violin Diagram of DME Disease-specific Protein Abundances |
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References | |||||
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1 | The Structural and functional characterization of mammalian ADP-dependent glucokinase. J Biol Chem. 2016 Feb 19;291(8):3694-704. |
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