| General Information of DME (ID: DMEN359) |
| DME Name |
Cytochrome P450 124A1 (cyp124A1), Mycobacterium tuberculosis
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| Gene Name |
cyp124A1
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| Lineage |
Species: Mycobacterium tuberculosis (Click to Show/Hide the Complete Species Lineage)
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Species: Mycobacterium tuberculosis
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Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Pathway/Function) of This DME
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| Full List of Drug(s) Metabolized by This DME |
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Drugs in Phase 2 Clinical Trial
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Click to Show/Hide the Full List of Drugs: 1 Drugs
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ANW-32821 |
Drug Info
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Phase 2 |
Cone rod dystrophy
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ICD11: 9B70
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[1], [2] |
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| Full List of Metabolic Reactions (MR) Catalyzed by This DME |
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| References |
| 1 |
Cholesterol ester oxidation by mycobacterial cytochrome P450. J Biol Chem. 2014 Oct 31;289(44):30417-25.
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| 2 |
Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets? Appl Microbiol Biotechnol. 2019 May;103(9):3597-3614.
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