Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007245)
Formula Reactant 27-hydroxycholesterol Product Carboxylic acid
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 124A1 (cyp124A1) DME Info
Steroid C26-monooxygenase (cyp125A1) DME Info
Steroid C26-monooxygenase (cyp142A1) DME Info
Cytochrome P450 124A1 (cyp124A1) DME Info
Cytochrome P450 125A1 (cyp125A1) DME Info
Cytochrome P450 142A1 (cyp142A1) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007244 ANW-32821 27-hydroxycholesterol Unclear ANW-32821 [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000605 PEG Carboxylic acid Unclear Certolizumab pegol [3]
References
1 Cholesterol ester oxidation by mycobacterial cytochrome P450. J Biol Chem. 2014 Oct 31;289(44):30417-25.
2 Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets? Appl Microbiol Biotechnol. 2019 May;103(9):3597-3614.
3 LABEL:CIMZIA- certolizumab pegol kit CIMZIA- certolizumab pegol injection

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