| General Information of Drug Metabolite (DM) (ID: DM000247) |
| DM Name |
Letrozole carbinol glucuronide metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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UDP-glucuronosyltransferase 2B7 (UGT2B7)
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DME0040
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| Conjugation - Glucuronidation |
Letrozole
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Letrozole |
DR0929
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Approved |
Breast cancer |
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| References |
| 1 |
The letrozole phase 1 metabolite carbinol as a novel probe drug for UGT2B7 Drug Metab Dispos. 2013 Nov;41(11):1906-13. doi: 10.1124/dmd.113.053405.
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