Details of the Drug Metabolite (DM) | INTEDE

General Information of Drug Metabolite (DM) (ID: DM000921)
DM Name	Ethinylestradiol-3,17-sulfate

Full List of Drug-Metabolizing Enzyme (DME) Related to This DM

DME(s) Producing This DM through Metabolism

DME Name	DME ID	Reactant	Reaction	Related Drug	REF
Carboxylesterase 1 (CES1)	DME0054	Ethinyl estradiol	Conjugation - Sulfation	Ethinyl estradiol	[1]
Sulfotransferase 1A3 (SULT1A3)	DME0063	Ethinyl estradiol	Conjugation - Sulfation	Ethinyl estradiol	[1]
Sulfotransferase 1A4 (SULT1A4)	DMEN007	Ethinyl estradiol	Conjugation - Sulfation	Ethinyl estradiol	[1]

Full List of Drug(s) That Produce This DM By Metabolism
Ethinyl estradiol		DR0656	Approved		Menopausal disorder

References
1	The pharmacokinetics and metabolism of ethinyl estradiol and its three sulfates in the baboon Am J Obstet Gynecol. 1983 May 1;146(1):80-7. doi: 10.1016/0002-9378(83)90931-6.

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