| General Information of Drug Metabolite (DM) (ID: DM000964) |
| DM Name |
39-O-desmethyl everolimus
|
|
|
|
|
|
|
|
| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
|
Cytochrome P450 3A4 (CYP3A4)
|
DME0001
|
| Oxidation - Demethylation |
Everolimus
|
[1] , [2] |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Full List of Drug(s) That Produce This DM By Metabolism |
| Everolimus |
DR0674
|
Approved |
Renal cell carcinoma |
|
|
| References |
| 1 |
Identification of everolimus metabolite patterns in trough blood samples of kidney transplant patients Ther Drug Monit. 2007 Oct;29(5):592-9. doi: 10.1097/FTD.0b013e3181570830.
|
| 2 |
Long-term cross-validation of everolimus therapeutic drug monitoring assays: the Zortracker study Ther Drug Monit. 2015 Jun;37(3):296-303. doi: 10.1097/FTD.0000000000000191.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.
