| General Information of Drug Metabolite (DM) (ID: DM001008) |
| DM Name |
Isoniazid reactive metabolite
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 2E1 (CYP2E1)
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DME0013
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| Unclear - Unclear |
Isoniazid
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[1] |
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N-acetyltransferase 2 (NAT2)
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DME0051
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| Unclear - Unclear |
Isoniazid
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Isoniazid |
DR0886
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Approved |
Pulmonary tuberculosis |
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| References |
| 1 |
Exploration of inhibition potential of isoniazid and its metabolites towards CYP2E1 in human liver microsomes through LC-MS/MS analysis J Pharm Biomed Anal. 2021 Sep 5;203:114223. doi: 10.1016/j.jpba.2021.114223.
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