| General Information of Drug Metabolite (DM) (ID: DM001327) |
| DM Name |
Oxidative metabolites
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| Full List of Drug-Metabolizing Enzyme (DME) Related to This DM |
| DME(s) Producing This DM through Metabolism |
| DME Name |
DME ID |
Reactant |
Reaction |
Related Drug |
REF |
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Cytochrome P450 3A4 (CYP3A4)
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DME0001
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| Oxidation - Oxidation |
Simeprevir sodium
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[1] |
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| Full List of Drug(s) That Produce This DM By Metabolism |
| Simeprevir sodium |
DR1484
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Approved |
Viral hepatitis |
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| References |
| 1 |
Hepatitis C virus direct-acting antiviral drug interactions and use in renal and hepatic impairment. Top Antivir Med. 2015 May-Jun;23(2):92-6.
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